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While individual practices vary from center to center, pituitary MRI studies usually include pre-contrast T1-weighted and T2-weighted spin-echo coronal and sagittal sections with thin slices. Coronal and/or sagittal T1-weighted spin-echo gadolinium-enhanced images are also often acquired. In order to gain the maximum amount of clinically useful information, the following items should be obtained: use of high matrix size (512), coronal spin-echo T1-weighted and fast spin-echo T2-weighted images, sagittal and axial T1-weighted images (to fully evaluate the posterior pituitary), and careful use of gadolinium contrast agents (30). Properly performed volumetric assessments can be helpful for follow-up of lesion progression, but these are often not performed in the routine setting when a sellar lesion is discovered by chance. While not used routinely, axial sequences can be of significant additional use in the differential diagnosis of certain sellar lesions. Diagnostic pitfalls can be avoided by using pulse sequences adapted for the sella and by recognizing artifacts such as magnetic susceptibility, partial volume, chemical shift or pulsatility. Occasionally some incidental findings may be variants of the normal pituitary.
The two types of article metrics we measure are (i) more traditional full-text views and pdf downloads, and (ii) Altmetric data, which shows the wider impact of articles in a range of non-traditional sources, such as social media.
The Topspin software is available to academic users free of charge for desktop processing. On the server there is an install directory. Copy the entire 4,2 GB image to your computer and then install the platform appropriate version. There are Mac, Windows and Linux variants within the image. If you need help setting up Topspin open a ticket with COSINE requesting help. They have a protocol that any of the support staff can guide you through
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